8018-3187 Screening compound: 2-[6-(thiophen-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl]pyrazine

8018-3187 Screening compound: 2-[6-(thiophen-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl]pyrazine
8018-3187 Screening compound: 2-[6-(thiophen-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl]pyrazine alternative view

Chemical Structure Depiction of ChemDiv screening compound 8018-3187
2-[6-(thiophen-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl]pyrazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8018-3187

Molecular Formula

C11H6N6S2 (C11 H6 N6 S2)

Compound Name

2-[6-(thiophen-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl]pyrazine

IUPAC name

2-[6-(thiophen-2-yl)-[124]triazolo[34-b][134]thiadiazol-3-yl]pyrazine

SMILES

c1csc(-c(s2)nn3c2nnc3-c2nccnc2)c1

InChI

InChI=1S/C11H6N6S2/c1-2-8(18-5-1)10-16-17-9(14-15-11(17)19-10)7-6-12-3-4-13-7/h1-6H

InChI Key

SUCWJRXAFZYKLV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD07400816

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

286.34

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.551

Distribution Coefficient, logD

1.551

Water Solubility, LogSw

-1.20

Polar Surface Area

53.306

Acid Dissociation Constant (pKa)

14.00

Base Dissociation Constant (pKb)

1.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

8018-3187 in Drug Discovery

Included in Screening Libraries

BRD4 Targeted Library (4534 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
  • Metabolic
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
Targets:
  • Others

References: we are preparing a list of scientific research reports with 8018-3187 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8018-3187?
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What is the minimum amount of 8018-3187 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8018-3187
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8018-3187
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8018-3187 available by request