8018-3505 Screening compound: 3'-[(pyridin-2-yl)carbamoyl]-[1,1'-biphenyl]-2-carboxylic acid

8018-3505 Screening compound: 3'-[(pyridin-2-yl)carbamoyl]-[1,1'-biphenyl]-2-carboxylic acid
8018-3505 Screening compound: 3'-[(pyridin-2-yl)carbamoyl]-[1,1'-biphenyl]-2-carboxylic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound 8018-3505
3'-[(pyridin-2-yl)carbamoyl]-[1,1'-biphenyl]-2-carboxylic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8018-3505

Molecular Formula

C19H14N2O3 (C19 H14 N2 O3)

Compound Name

3'-[(pyridin-2-yl)carbamoyl]-[1,1'-biphenyl]-2-carboxylic acid

IUPAC name

3'-[(pyridin-2-yl)carbamoyl]-[11'-biphenyl]-2-carboxylic acid

SMILES

OC(c(cccc1)c1-c1cc(C(Nc2ncccc2)=O)ccc1)=O

InChI

InChI=1S/C19H14N2O3/c22-18(21-17-10-3-4-11-20-17)14-7-5-6-13(12-14)15-8-1-2-9-16(15)19(23)24/h1-12H,(H,23,24)(H,20,21,22)

InChI Key

CVBXXDXTJJFEOJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD07658149

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

318.33

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.476

Distribution Coefficient, logD

0.301

Water Solubility, LogSw

-3.78

Polar Surface Area

61.081

Acid Dissociation Constant (pKa)

4.23

Base Dissociation Constant (pKb)

3.19

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

8018-3505 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Targets:
  • Proteases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with 8018-3505 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8018-3505?
Check Price and Availability of 8018-3505, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8018-3505 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8018-3505
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8018-3505
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8018-3505 available by request