8018-4260 Screening compound: 4-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,3-thiazol-2-amine

8018-4260 Screening compound: 4-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,3-thiazol-2-amine
8018-4260 Screening compound: 4-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,3-thiazol-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound 8018-4260
4-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,3-thiazol-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8018-4260

Molecular Formula

C11H10N2O2S (C11 H10 N2 O2 S)

Compound Name

4-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,3-thiazol-2-amine

IUPAC name

4-(23-dihydro-14-benzodioxin-6-yl)-13-thiazol-2-amine

SMILES

Nc1nc(-c(cc2)cc3c2OCCO3)cs1

InChI

InChI=1S/C11H10N2O2S/c12-11-13-8(6-16-11)7-1-2-9-10(5-7)15-4-3-14-9/h1-2,5-6H,3-4H2,(H2,12,13)

InChI Key

QNDNSJKGUGRQDK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00807205

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

234.28

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

1.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

1.553

Distribution Coefficient, logD

1.551

Water Solubility, LogSw

-2.20

Polar Surface Area

46.593

Acid Dissociation Constant (pKa)

21.44

Base Dissociation Constant (pKb)

5.00

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

8018-4260 in Drug Discovery

Included in Screening Libraries

Antiparasite Library (23996 compounds)

Antiviral Annotated Library (21441 compounds)

Fragments Library (11262 compounds)

Human Receptors Annotated Library (5376 compounds)

Soluble Diversity Library (15920 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Ion Channels Focused Library (26372 compounds)

Receptor-type Protein Tyrosine Phosphatases Library (3746 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Nervous system
  • Cardiovascular
  • Cancer
  • Digestive system
  • Nervous system
  • Female
  • Metabolic
  • Endocrine
Agro:
  • Agro
Structure:
  • Fragments
Targets:
  • Ion Channels
  • Phosphatases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 8018-4260 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8018-4260?
Check Price and Availability of 8018-4260, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8018-4260 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8018-4260
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8018-4260
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8018-4260 available by request