8018-7514 Screening compound: 2-[3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl]pyrazine

8018-7514 Screening compound: 2-[3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl]pyrazine
8018-7514 Screening compound: 2-[3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl]pyrazine alternative view

Chemical Structure Depiction of ChemDiv screening compound 8018-7514
2-[3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl]pyrazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8018-7514

Molecular Formula

C11H7N5O (C11 H7 N5 O)

Compound Name

2-[3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl]pyrazine

IUPAC name

2-[3-(pyridin-4-yl)-124-oxadiazol-5-yl]pyrazine

SMILES

c1cnccc1-c1noc(-c2nccnc2)n1

InChI

InChI=1S/C11H7N5O/c1-3-12-4-2-8(1)10-15-11(17-16-10)9-7-13-5-6-14-9/h1-7H

InChI Key

ISKQEBAKTVONNJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08142943

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

225.21

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.044

Distribution Coefficient, logD

1.043

Water Solubility, LogSw

-0.83

Polar Surface Area

59.638

Acid Dissociation Constant (pKa)

14.00

Base Dissociation Constant (pKb)

3.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

8018-7514 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Fragments Library (11262 compounds)

GABA Library (7115 compounds)

Included in 1.7M Stock Database

Structure:
  • Fragments
Therapeutical areas:
  • Eye
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 8018-7514 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8018-7514?
Check Price and Availability of 8018-7514, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8018-7514 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8018-7514
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8018-7514
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8018-7514 available by request