8018-9183 Screening compound: ethyl 6,8-difluoro-4-hydroxyquinoline-3-carboxylate

8018-9183 Screening compound: ethyl 6,8-difluoro-4-hydroxyquinoline-3-carboxylate
8018-9183 Screening compound: ethyl 6,8-difluoro-4-hydroxyquinoline-3-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound 8018-9183
ethyl 6,8-difluoro-4-hydroxyquinoline-3-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8018-9183

Molecular Formula

C12H9F2NO3 (C12 H9 F2 NO3)

Compound Name

ethyl 6,8-difluoro-4-hydroxyquinoline-3-carboxylate

IUPAC name

ethyl 68-difluoro-4-hydroxyquinoline-3-carboxylate

SMILES

CCOC(c1cnc2c(F)cc(F)cc2c1O)=O

InChI

InChI=1S/C12H9F2NO3/c1-2-18-12(17)8-5-15-10-7(11(8)16)3-6(13)4-9(10)14/h3-5H,2H2,1H3,(H,15,16)

InChI Key

NUHKASXLPYOGHW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD00173349

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

253.21

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

2.938

Distribution Coefficient, logD

2.781

Water Solubility, LogSw

-2.97

Polar Surface Area

46.094

Acid Dissociation Constant (pKa)

7.76

Base Dissociation Constant (pKb)

-0.95

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

8018-9183 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

GABA Library (7115 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Eye
Mechanism of action:
  • Epigenetic
  • Receptor's ligands
Targets:
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with 8018-9183 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8018-9183?
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What is the minimum amount of 8018-9183 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8018-9183
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8018-9183
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8018-9183 available by request