8018-9268 Screening compound: 6-{[6-bromo-3,4-dihydro-1(2H)-quinolinyl]sulfonyl}-7-methyl-2H-1,4-benzoxazin-3(4H)-one

8018-9268 Screening compound: 6-{[6-bromo-3,4-dihydro-1(2H)-quinolinyl]sulfonyl}-7-methyl-2H-1,4-benzoxazin-3(4H)-one
8018-9268 Screening compound: 6-{[6-bromo-3,4-dihydro-1(2H)-quinolinyl]sulfonyl}-7-methyl-2H-1,4-benzoxazin-3(4H)-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 8018-9268
6-{[6-bromo-3,4-dihydro-1(2H)-quinolinyl]sulfonyl}-7-methyl-2H-1,4-benzoxazin-3(4H)-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8018-9268

Molecular Formula

C18H17BrN2O4S (C18 H17 BrN2 O4 S)

Compound Name

6-{[6-bromo-3,4-dihydro-1(2H)-quinolinyl]sulfonyl}-7-methyl-2H-1,4-benzoxazin-3(4H)-one

IUPAC name

6-[(6-bromo-1234-tetrahydroquinolin-1-yl)sulfonyl]-7-methyl-34-dihydro-2H-14-benzoxazin-3-one

SMILES

Cc(cc(c(N1)c2)OCC1=O)c2S(N(CCC1)c(cc2)c1cc2Br)(=O)=O

InChI

InChI=1S/C18H17BrN2O4S/c1-11-7-16-14(20-18(22)10-25-16)9-17(11)26(23,24)21-6-2-3-12-8-13(19)4-5-15(12)21/h4-5,7-9H,2-3,6,10H2,1H3,(H,20,22)

InChI Key

ZXUWBKGTBPRLBG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09063081

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

437.31

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.831

Distribution Coefficient, logD

2.831

Water Solubility, LogSw

-3.41

Polar Surface Area

64.661

Acid Dissociation Constant (pKa)

10.67

Base Dissociation Constant (pKb)

-2.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.78

8018-9268 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antiparasite Library (23996 compounds)

Antiviral Library (67538 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Agro:
  • Agro
  • Agro
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with 8018-9268 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8018-9268?
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What is the minimum amount of 8018-9268 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8018-9268
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8018-9268
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8018-9268 available by request