8019-0297 Screening compound: 1-[4-(3-fluorophenyl)-2-methyl-1,4-dihydropyrimido[1,2-a][1,3]benzimidazol-3-yl]-1-ethanone

8019-0297 Screening compound: 1-[4-(3-fluorophenyl)-2-methyl-1,4-dihydropyrimido[1,2-a][1,3]benzimidazol-3-yl]-1-ethanone
8019-0297 Screening compound: 1-[4-(3-fluorophenyl)-2-methyl-1,4-dihydropyrimido[1,2-a][1,3]benzimidazol-3-yl]-1-ethanone alternative view

Chemical Structure Depiction of ChemDiv screening compound 8019-0297
1-[4-(3-fluorophenyl)-2-methyl-1,4-dihydropyrimido[1,2-a][1,3]benzimidazol-3-yl]-1-ethanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8019-0297

Molecular Formula

C19H16FN3O (C19 H16 FN3 O)

Compound Name

1-[4-(3-fluorophenyl)-2-methyl-1,4-dihydropyrimido[1,2-a][1,3]benzimidazol-3-yl]-1-ethanone

IUPAC name

1-[13-(3-fluorophenyl)-11-methyl-1810-triazatricyclo[7.4.0.0^{27}]trideca-2(7)35811-pentaen-12-yl]ethan-1-one

SMILES

CC(C1=C(C)Nc2nc(cccc3)c3n2C1c1cccc(F)c1)=O

InChI

InChI=1S/C19H16FN3O/c1-11-17(12(2)24)18(13-6-5-7-14(20)10-13)23-16-9-4-3-8-15(16)22-19(23)21-11/h3-10,18H,1-2H3,(H,21,22)/t18-/m0/s1

InChI Key

QJQDOXXDPHELNM-SFHVURJKSA-N

MDL Number (MFCD)

MFCD08592489

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

321.35

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.735

Distribution Coefficient, logD

3.733

Water Solubility, LogSw

-3.95

Polar Surface Area

37.861

Acid Dissociation Constant (pKa)

9.71

Base Dissociation Constant (pKb)

0.58

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

15.80

8019-0297 in Drug Discovery

Included in Screening Libraries

DGK Inhibitors Library (10558 compounds)

Nucleic Acid Ligands (8311 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 8019-0297 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8019-0297?
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What is the minimum amount of 8019-0297 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8019-0297
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8019-0297
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8019-0297 available by request