8019-4512 Screening compound: 5-amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylic acid

8019-4512 Screening compound: 5-amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylic acid
8019-4512 Screening compound: 5-amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound 8019-4512
5-amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8019-4512

Molecular Formula

C10H8FN3O2 (C10 H8 FN3 O2)

Compound Name

5-amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylic acid

IUPAC name

5-amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylic acid

SMILES

Nc(n(-c(cc1)ccc1F)nc1)c1C(O)=O

InChI

InChI=1S/C10H8FN3O2/c11-6-1-3-7(4-2-6)14-9(12)8(5-13-14)10(15)16/h1-5H,12H2,(H,15,16)

InChI Key

MZPQLGKWWLMKEO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01569434

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

221.19

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

1.593

Distribution Coefficient, logD

-3.695

Water Solubility, LogSw

-1.99

Polar Surface Area

61.963

Acid Dissociation Constant (pKa)

2.11

Base Dissociation Constant (pKb)

-2.61

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

8019-4512 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Fragments Library (11262 compounds)

GABA Library (7115 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Eye
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Mechanism of action:
  • Epigenetic
  • Receptor's ligands
Structure:
  • Fragments
Targets:
  • GPCR
  • Ion Channels
  • Phosphatases

References: we are preparing a list of scientific research reports with 8019-4512 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8019-4512?
Check Price and Availability of 8019-4512, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8019-4512 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8019-4512
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8019-4512
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8019-4512 available by request