8019-5860 Screening compound: 3-(4-chlorophenyl)-5-(3,4-dimethoxyphenyl)-2-(methoxymethyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
Chemical Structure Depiction of ChemDiv screening compound 8019-5860
3-(4-chlorophenyl)-5-(3,4-dimethoxyphenyl)-2-(methoxymethyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
Available from 1 mg
Formats:
- Glass Vials (4ml Glass Vials VWR #97047-678)
- 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)
Shiptime: 1 week worldwide delivery in most cases
Compound Identifiers
ChemDiv Compound ID
8019-5860
Molecular Formula
C23H19ClF3N3O3 (C23 H19 ClF3 N3 O3)
Compound Name
3-(4-chlorophenyl)-5-(3,4-dimethoxyphenyl)-2-(methoxymethyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
IUPAC name
3-(4-chlorophenyl)-5-(34-dimethoxyphenyl)-2-(methoxymethyl)-7-(trifluoromethyl)pyrazolo[15-a]pyrimidine
SMILES
COCc1nn2c(C(F)(F)F)cc(-c(cc3)cc(OC)c3OC)nc2c1-c(cc1)ccc1Cl
InChI Key
MDL Number (MFCD)
Chemical and Physical Properties
Saltdata
n/a
Molecular Weight
477.87
Hydrogen Bond Acceptors Count
5.00
Hydrogen Bond Donors Count
0.00
Rotatable Bond Count
7.00
Number of Nitrogen and Oxygen Atoms
6
Partition Coefficient, logP
5.431
Distribution Coefficient, logD
5.430
Water Solubility, LogSw
-6.33
Polar Surface Area
43.623
Acid Dissociation Constant (pKa)
28.03
Base Dissociation Constant (pKb)
4.68
Number of Chiral Centers
0.00
Percent sp3 carbon bonding
21.70
8019-5860 in Drug Discovery
Included in Screening Libraries
3D-Pharmacophore Based Diversity Library (49813 compounds)
Anti-Inflammatory Library (24602 compounds)
Included in 1.7M Stock Database
- Immune system
References: we are preparing a list of scientific research reports with 8019-5860 chemical compound. It will be published here after verification.
Frequently Asked Questions
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Available from 1 mg in Glass Vials or 96-tube racks.
ChemDiv sends parcels with Express services (UPS, WC).
- 1–2 days for small orders
- 2–4 weeks for large selections
- 0.5–50 mg of dry powder sample in single glass vials, custom vials
- DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)