8020-2980 Screening compound: 1-[4-azido-5-(hydroxymethyl)oxolan-2-yl]-4-(ethylamino)-5-methyl-1,2-dihydropyrimidin-2-one

8020-2980 Screening compound: 1-[4-azido-5-(hydroxymethyl)oxolan-2-yl]-4-(ethylamino)-5-methyl-1,2-dihydropyrimidin-2-one
8020-2980 Screening compound: 1-[4-azido-5-(hydroxymethyl)oxolan-2-yl]-4-(ethylamino)-5-methyl-1,2-dihydropyrimidin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 8020-2980
1-[4-azido-5-(hydroxymethyl)oxolan-2-yl]-4-(ethylamino)-5-methyl-1,2-dihydropyrimidin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8020-2980

Molecular Formula

C12H18N6O3 (C12 H18 N6 O3)

Compound Name

1-[4-azido-5-(hydroxymethyl)oxolan-2-yl]-4-(ethylamino)-5-methyl-1,2-dihydropyrimidin-2-one

IUPAC name

1-[(2R5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-4-(ethylamino)-5-methyl-12-dihydropyrimidin-2-one

SMILES

CCNC(C(C)=CN1[C@H](C2)O[C@@H](CO)C2N=[N+]=[N-])=NC1=O

InChI

InChI=1S/C12H18N6O3/c1-3-14-11-7(2)5-18(12(20)15-11)10-4-8(16-17-13)9(6-19)21-10/h5,8-10,19H,3-4,6H2,1-2H3,(H,14,15,20)/t8?,9-,10+/m1/s1

InChI Key

TXRRVNODEOVMHL-XVBQNVSMSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

294.31

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

0.365

Distribution Coefficient, logD

0.364

Water Solubility, LogSw

-1.16

Polar Surface Area

103.785

Acid Dissociation Constant (pKa)

14.06

Base Dissociation Constant (pKb)

3.34

Number of Chiral Centers

3.00

Percent sp3 carbon bonding

66.70

8020-2980 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Nucleoside Mimetics Library (2197 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Cancer
  • Immune system
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with 8020-2980 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8020-2980?
Check Price and Availability of 8020-2980, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8020-2980 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8020-2980
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8020-2980
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8020-2980 available by request