8020-7526 Screening compound: 5-(3-bromophenyl)-4-(2-furylcarbonyl)-3-hydroxy-1-(1,3-thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one

8020-7526 Screening compound: 5-(3-bromophenyl)-4-(2-furylcarbonyl)-3-hydroxy-1-(1,3-thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one
8020-7526 Screening compound: 5-(3-bromophenyl)-4-(2-furylcarbonyl)-3-hydroxy-1-(1,3-thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound 8020-7526
5-(3-bromophenyl)-4-(2-furylcarbonyl)-3-hydroxy-1-(1,3-thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8020-7526

Molecular Formula

C18H11BrN2O4S (C18 H11 BrN2 O4 S)

Compound Name

5-(3-bromophenyl)-4-(2-furylcarbonyl)-3-hydroxy-1-(1,3-thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one

IUPAC name

5-(3-bromophenyl)-4-(furan-2-carbonyl)-3-hydroxy-1-(13-thiazol-2-yl)-25-dihydro-1H-pyrrol-2-one

SMILES

OC(C(N(C1c2cccc(Br)c2)c2nccs2)=O)=C1C(c1ccco1)=O

InChI

InChI=1S/C18H11BrN2O4S/c19-11-4-1-3-10(9-11)14-13(15(22)12-5-2-7-25-12)16(23)17(24)21(14)18-20-6-8-26-18/h1-9,14,23H/t14-/m1/s1

InChI Key

OCAXLZUOGBYOGG-CQSZACIVSA-N

MDL Number (MFCD)

MFCD30711315

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

431.27

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.274

Distribution Coefficient, logD

2.679

Water Solubility, LogSw

-3.36

Polar Surface Area

63.046

Acid Dissociation Constant (pKa)

6.93

Base Dissociation Constant (pKb)

-3.96

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

5.56

8020-7526 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with 8020-7526 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8020-7526?
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What is the minimum amount of 8020-7526 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8020-7526
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8020-7526
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8020-7526 available by request