8104-10718 Screening compound: 3-(4-chlorophenyl)-6-(3,4-dimethoxyphenyl)-2-methylpyrazolo[1,5-a]pyrimidin-7-amine

8104-10718 Screening compound: 3-(4-chlorophenyl)-6-(3,4-dimethoxyphenyl)-2-methylpyrazolo[1,5-a]pyrimidin-7-amine
8104-10718 Screening compound: 3-(4-chlorophenyl)-6-(3,4-dimethoxyphenyl)-2-methylpyrazolo[1,5-a]pyrimidin-7-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound 8104-10718
3-(4-chlorophenyl)-6-(3,4-dimethoxyphenyl)-2-methylpyrazolo[1,5-a]pyrimidin-7-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8104-10718

Molecular Formula

C21H19ClN4O2 (C21 H19 ClN4 O2)

Compound Name

3-(4-chlorophenyl)-6-(3,4-dimethoxyphenyl)-2-methylpyrazolo[1,5-a]pyrimidin-7-amine

IUPAC name

3-(4-chlorophenyl)-6-(34-dimethoxyphenyl)-2-methylpyrazolo[15-a]pyrimidin-7-amine

SMILES

Cc(c(-c(cc1)ccc1Cl)c1nc2)nn1c(N)c2-c(cc1)cc(OC)c1OC

InChI

InChI=1S/C21H19ClN4O2/c1-12-19(13-4-7-15(22)8-5-13)21-24-11-16(20(23)26(21)25-12)14-6-9-17(27-2)18(10-14)28-3/h4-11H,23H2,1-3H3

InChI Key

MJRRVLNFMDNPFH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14713304

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

394.86

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.660

Distribution Coefficient, logD

3.450

Water Solubility, LogSw

-4.67

Polar Surface Area

55.029

Acid Dissociation Constant (pKa)

19.94

Base Dissociation Constant (pKb)

7.19

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

8104-10718 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Antimitotic Tubulin Library (17355 compounds)

C-Met Library (15277 compounds)

CNS Targets (44014 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 8104-10718 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8104-10718?
Check Price and Availability of 8104-10718, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8104-10718 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8104-10718
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8104-10718
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8104-10718 available by request