8173-0140 Screening compound: 3-(3-chlorophenyl)-5-(3,4-dimethoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine

8173-0140 Screening compound: 3-(3-chlorophenyl)-5-(3,4-dimethoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
8173-0140 Screening compound: 3-(3-chlorophenyl)-5-(3,4-dimethoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound 8173-0140
3-(3-chlorophenyl)-5-(3,4-dimethoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8173-0140

Molecular Formula

C21H15ClF3N3O2 (C21 H15 ClF3 N3 O2)

Compound Name

3-(3-chlorophenyl)-5-(3,4-dimethoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine

IUPAC name

3-(3-chlorophenyl)-5-(34-dimethoxyphenyl)-7-(trifluoromethyl)pyrazolo[15-a]pyrimidine

SMILES

COc(ccc(-c(cc(C(F)(F)F)n1nc2)nc1c2-c1cccc(Cl)c1)c1)c1OC

InChI

InChI=1S/C21H15ClF3N3O2/c1-29-17-7-6-13(9-18(17)30-2)16-10-19(21(23,24)25)28-20(27-16)15(11-26-28)12-4-3-5-14(22)8-12/h3-11H,1-2H3

InChI Key

ACOKHYZXXBNOTD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08681167

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

433.82

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.743

Distribution Coefficient, logD

5.742

Water Solubility, LogSw

-6.14

Polar Surface Area

34.157

Acid Dissociation Constant (pKa)

32.86

Base Dissociation Constant (pKb)

4.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

8173-0140 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 8173-0140 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8173-0140?
Check Price and Availability of 8173-0140, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8173-0140 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8173-0140
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8173-0140
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8173-0140 available by request