8188-0899 Screening compound: N-[3-(5-methoxy-1,3-benzoxazol-2-yl)phenyl]-2,2-diphenylacetamide

8188-0899 Screening compound: N-[3-(5-methoxy-1,3-benzoxazol-2-yl)phenyl]-2,2-diphenylacetamide
8188-0899 Screening compound: N-[3-(5-methoxy-1,3-benzoxazol-2-yl)phenyl]-2,2-diphenylacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8188-0899
N-[3-(5-methoxy-1,3-benzoxazol-2-yl)phenyl]-2,2-diphenylacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8188-0899

Molecular Formula

C28H22N2O3 (C28 H22 N2 O3)

Compound Name

N-[3-(5-methoxy-1,3-benzoxazol-2-yl)phenyl]-2,2-diphenylacetamide

IUPAC name

N-[3-(5-methoxy-13-benzoxazol-2-yl)phenyl]-22-diphenylacetamide

SMILES

COc(cc1)cc2c1oc(-c1cccc(NC(C(c3ccccc3)c3ccccc3)=O)c1)n2

InChI

InChI=1S/C28H22N2O3/c1-32-23-15-16-25-24(18-23)30-28(33-25)21-13-8-14-22(17-21)29-27(31)26(19-9-4-2-5-10-19)20-11-6-3-7-12-20/h2-18,26H,1H3,(H,29,31)

InChI Key

IZUYDWHANMHXBC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05796799

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

434.49

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.142

Distribution Coefficient, logD

6.142

Water Solubility, LogSw

-5.65

Polar Surface Area

47.412

Acid Dissociation Constant (pKa)

11.88

Base Dissociation Constant (pKb)

0.70

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

7.10

8188-0899 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

DGK Inhibitors Library (10558 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with 8188-0899 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8188-0899?
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What is the minimum amount of 8188-0899 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8188-0899
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8188-0899
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8188-0899 available by request