8228-0471 Screening compound: 2-[(1E)-2-(5-iodo-2-methoxyphenyl)ethenyl]quinolin-8-ol

8228-0471 Screening compound: 2-[(1E)-2-(5-iodo-2-methoxyphenyl)ethenyl]quinolin-8-ol
8228-0471 Screening compound: 2-[(1E)-2-(5-iodo-2-methoxyphenyl)ethenyl]quinolin-8-ol alternative view

Chemical Structure Depiction of ChemDiv screening compound 8228-0471
2-[(1E)-2-(5-iodo-2-methoxyphenyl)ethenyl]quinolin-8-ol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8228-0471

Molecular Formula

C18H14INO2 (C18 H14 INO2)

Compound Name

2-[(1E)-2-(5-iodo-2-methoxyphenyl)ethenyl]quinolin-8-ol

IUPAC name

2-[(1E)-2-(5-iodo-2-methoxyphenyl)ethenyl]quinolin-8-ol

SMILES

COc(cc1)c(/C=C/c(ccc2ccc3)nc2c3O)cc1I

InChI

InChI=1S/C18H14INO2/c1-22-17-10-7-14(19)11-13(17)6-9-15-8-5-12-3-2-4-16(21)18(12)20-15/h2-11,21H,1H3

InChI Key

POBKAENWLMKZDT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06000350

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

403.22

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

5.830

Distribution Coefficient, logD

5.825

Water Solubility, LogSw

-6.36

Polar Surface Area

33.742

Acid Dissociation Constant (pKa)

9.41

Base Dissociation Constant (pKb)

3.86

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.60

8228-0471 in Drug Discovery

Included in Screening Libraries

Antiviral Annotated Library (21441 compounds)

Human Kinases Annotated Library (2415 compounds)

Human Receptors Annotated Library (5376 compounds)

Human Transcription Factors Annotated Library (5098 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with 8228-0471 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8228-0471?
Check Price and Availability of 8228-0471, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8228-0471 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8228-0471
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8228-0471
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8228-0471 available by request