8264-0685 Screening compound: N-[3-(propan-2-yloxy)propyl]-4-[(1,2,3,4-tetrahydroisoquinolin-2-yl)methyl]benzamide

8264-0685 Screening compound: N-[3-(propan-2-yloxy)propyl]-4-[(1,2,3,4-tetrahydroisoquinolin-2-yl)methyl]benzamide
8264-0685 Screening compound: N-[3-(propan-2-yloxy)propyl]-4-[(1,2,3,4-tetrahydroisoquinolin-2-yl)methyl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8264-0685
N-[3-(propan-2-yloxy)propyl]-4-[(1,2,3,4-tetrahydroisoquinolin-2-yl)methyl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8264-0685

Molecular Formula

C23H30N2O2 (C23 H30 N2 O2)

Compound Name

N-[3-(propan-2-yloxy)propyl]-4-[(1,2,3,4-tetrahydroisoquinolin-2-yl)methyl]benzamide

IUPAC name

N-[3-(propan-2-yloxy)propyl]-4-[(1234-tetrahydroisoquinolin-2-yl)methyl]benzamide

SMILES

CC(C)OCCCNC(c1ccc(CN(CC2)Cc3c2cccc3)cc1)=O

InChI

InChI=1S/C23H30N2O2/c1-18(2)27-15-5-13-24-23(26)21-10-8-19(9-11-21)16-25-14-12-20-6-3-4-7-22(20)17-25/h3-4,6-11,18H,5,12-17H2,1-2H3,(H,24,26)

InChI Key

ZSSMKULOPVHPSY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04362922

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

366.5

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.275

Distribution Coefficient, logD

2.994

Water Solubility, LogSw

-3.41

Polar Surface Area

35.360

Acid Dissociation Constant (pKa)

14.11

Base Dissociation Constant (pKb)

7.36

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

43.50

8264-0685 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Dark Chemical Matter Library (18430 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Nervous system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Kinases
  • GPCR
  • Ion Channels
  • Others
Structure:
  • Pool
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with 8264-0685 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8264-0685?
Check Price and Availability of 8264-0685, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8264-0685 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8264-0685
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8264-0685
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8264-0685 available by request