8323-0276 Screening compound: 3-(5-{imidazo[1,2-a]pyrimidin-2-yl}-2-methoxyphenyl)-1-(4-methoxyphenyl)urea

8323-0276 Screening compound: 3-(5-{imidazo[1,2-a]pyrimidin-2-yl}-2-methoxyphenyl)-1-(4-methoxyphenyl)urea
8323-0276 Screening compound: 3-(5-{imidazo[1,2-a]pyrimidin-2-yl}-2-methoxyphenyl)-1-(4-methoxyphenyl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound 8323-0276
3-(5-{imidazo[1,2-a]pyrimidin-2-yl}-2-methoxyphenyl)-1-(4-methoxyphenyl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8323-0276

Molecular Formula

C21H19N5O3 (C21 H19 N5 O3)

Compound Name

3-(5-{imidazo[1,2-a]pyrimidin-2-yl}-2-methoxyphenyl)-1-(4-methoxyphenyl)urea

IUPAC name

3-(5-{imidazo[12-a]pyrimidin-2-yl}-2-methoxyphenyl)-1-(4-methoxyphenyl)urea

SMILES

COc(cc1)ccc1NC(Nc(cc(cc1)-c2cn(cccn3)c3n2)c1OC)=O

InChI

InChI=1S/C21H19N5O3/c1-28-16-7-5-15(6-8-16)23-21(27)25-17-12-14(4-9-19(17)29-2)18-13-26-11-3-10-22-20(26)24-18/h3-13H,1-2H3,(H2,23,25,27)

InChI Key

WZJGNHBOKZQRGC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06433580

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

389.41

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.285

Distribution Coefficient, logD

3.285

Water Solubility, LogSw

-3.56

Polar Surface Area

66.889

Acid Dissociation Constant (pKa)

12.84

Base Dissociation Constant (pKb)

3.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.50

8323-0276 in Drug Discovery

Included in Screening Libraries

Immunological Library (6760 compounds)

Protein-Protein Interaction Library (218420 compounds)

Selective Target Activity Profiling Library (14702 compounds)

SmartTM Library (51161 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with 8323-0276 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8323-0276?
Check Price and Availability of 8323-0276, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8323-0276 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8323-0276
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8323-0276
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8323-0276 available by request