8335-0334 Screening compound: 5-(benzenesulfonyl)-N4-(4-methoxyphenyl)-2-methylpyrimidine-4,6-diamine

8335-0334 Screening compound: 5-(benzenesulfonyl)-N4-(4-methoxyphenyl)-2-methylpyrimidine-4,6-diamine
8335-0334 Screening compound: 5-(benzenesulfonyl)-N4-(4-methoxyphenyl)-2-methylpyrimidine-4,6-diamine alternative view

Chemical Structure Depiction of ChemDiv screening compound 8335-0334
5-(benzenesulfonyl)-N4-(4-methoxyphenyl)-2-methylpyrimidine-4,6-diamine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8335-0334

Molecular Formula

C18H18N4O3S (C18 H18 N4 O3 S)

Compound Name

5-(benzenesulfonyl)-N4-(4-methoxyphenyl)-2-methylpyrimidine-4,6-diamine

IUPAC name

n/a

SMILES

Cc(nc1N)nc(Nc(cc2)ccc2OC)c1S(c1ccccc1)(=O)=O

InChI

InChI=1S/C18H18N4O3S/c1-12-20-17(19)16(26(23,24)15-6-4-3-5-7-15)18(21-12)22-13-8-10-14(25-2)11-9-13/h3-11H,1-2H3,(H3,19,20,21,22)

InChI Key

OVZCVNHDCQYQDZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD07758263

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

370.43

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.630

Distribution Coefficient, logD

2.630

Water Solubility, LogSw

-3.24

Polar Surface Area

85.716

Acid Dissociation Constant (pKa)

17.44

Base Dissociation Constant (pKb)

1.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

8335-0334 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

C-Met Library (15277 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Immune system
Agro:
  • Agro
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 8335-0334 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8335-0334?
Check Price and Availability of 8335-0334, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8335-0334 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8335-0334
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8335-0334
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8335-0334 available by request