8343-0269 Screening compound: 3-(4-chlorophenyl)-7-{[(3-chlorophenyl)methyl]sulfanyl}-1H,2H,3H,4H-[1,3]diazino[4,5-d]pyrimidine-2,4-dione

8343-0269 Screening compound: 3-(4-chlorophenyl)-7-{[(3-chlorophenyl)methyl]sulfanyl}-1H,2H,3H,4H-[1,3]diazino[4,5-d]pyrimidine-2,4-dione
8343-0269 Screening compound: 3-(4-chlorophenyl)-7-{[(3-chlorophenyl)methyl]sulfanyl}-1H,2H,3H,4H-[1,3]diazino[4,5-d]pyrimidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound 8343-0269
3-(4-chlorophenyl)-7-{[(3-chlorophenyl)methyl]sulfanyl}-1H,2H,3H,4H-[1,3]diazino[4,5-d]pyrimidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8343-0269

Molecular Formula

C19H12Cl2N4O2S (C19 H12 Cl2 N4 O2 S)

Compound Name

3-(4-chlorophenyl)-7-{[(3-chlorophenyl)methyl]sulfanyl}-1H,2H,3H,4H-[1,3]diazino[4,5-d]pyrimidine-2,4-dione

IUPAC name

3-(4-chlorophenyl)-7-{[(3-chlorophenyl)methyl]sulfanyl}-1H2H3H4H-[13]diazino[45-d]pyrimidine-24-dione

SMILES

O=C(c(cn1)c(N2)nc1SCc1cccc(Cl)c1)N(c(cc1)ccc1Cl)C2=O

InChI

InChI=1S/C19H12Cl2N4O2S/c20-12-4-6-14(7-5-12)25-17(26)15-9-22-18(23-16(15)24-19(25)27)28-10-11-2-1-3-13(21)8-11/h1-9H,10H2,(H,22,23,24,27)

InChI Key

ZUVSIAQPGNXKNR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06755246

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

431.3

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.469

Distribution Coefficient, logD

3.125

Water Solubility, LogSw

-4.67

Polar Surface Area

57.988

Acid Dissociation Constant (pKa)

6.08

Base Dissociation Constant (pKb)

-1.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.30

8343-0269 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

C-Met Library (15277 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with 8343-0269 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8343-0269?
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What is the minimum amount of 8343-0269 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8343-0269
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8343-0269
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8343-0269 available by request