8377-0266 Screening compound: N-[2-chloro-5-(5-methyl-1,3-benzoxazol-2-yl)phenyl]-2-methylpropanamide

8377-0266 Screening compound: N-[2-chloro-5-(5-methyl-1,3-benzoxazol-2-yl)phenyl]-2-methylpropanamide
8377-0266 Screening compound: N-[2-chloro-5-(5-methyl-1,3-benzoxazol-2-yl)phenyl]-2-methylpropanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8377-0266
N-[2-chloro-5-(5-methyl-1,3-benzoxazol-2-yl)phenyl]-2-methylpropanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8377-0266

Molecular Formula

C18H17ClN2O2 (C18 H17 ClN2 O2)

Compound Name

N-[2-chloro-5-(5-methyl-1,3-benzoxazol-2-yl)phenyl]-2-methylpropanamide

IUPAC name

N-[2-chloro-5-(5-methyl-13-benzoxazol-2-yl)phenyl]-2-methylpropanamide

SMILES

CC(C)C(Nc(cc(cc1)-c2nc(cc(C)cc3)c3o2)c1Cl)=O

InChI

InChI=1S/C18H17ClN2O2/c1-10(2)17(22)20-14-9-12(5-6-13(14)19)18-21-15-8-11(3)4-7-16(15)23-18/h4-10H,1-3H3,(H,20,22)

InChI Key

CRCMZEXMJVVXNM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03453828

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

328.8

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.818

Distribution Coefficient, logD

4.818

Water Solubility, LogSw

-4.94

Polar Surface Area

39.714

Acid Dissociation Constant (pKa)

11.24

Base Dissociation Constant (pKb)

-0.85

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

8377-0266 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Antifungal Library (16415 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Mechanism of action:
  • Epigenetic
  • Receptor's ligands
Agro:
  • Agro
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 8377-0266 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8377-0266?
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What is the minimum amount of 8377-0266 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8377-0266
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8377-0266
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8377-0266 available by request