8377-1555 Screening compound: 3-chloro-N-(2-methylquinolin-8-yl)-1-benzothiophene-2-carboxamide

8377-1555 Screening compound: 3-chloro-N-(2-methylquinolin-8-yl)-1-benzothiophene-2-carboxamide
8377-1555 Screening compound: 3-chloro-N-(2-methylquinolin-8-yl)-1-benzothiophene-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound 8377-1555
3-chloro-N-(2-methylquinolin-8-yl)-1-benzothiophene-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8377-1555

Molecular Formula

C19H13ClN2OS (C19 H13 ClN2 OS)

Compound Name

3-chloro-N-(2-methylquinolin-8-yl)-1-benzothiophene-2-carboxamide

IUPAC name

3-chloro-N-(2-methylquinolin-8-yl)-1-benzothiophene-2-carboxamide

SMILES

Cc1ccc(cccc2NC(c(sc3c4cccc3)c4Cl)=O)c2n1

InChI

InChI=1S/C19H13ClN2OS/c1-11-9-10-12-5-4-7-14(17(12)21-11)22-19(23)18-16(20)13-6-2-3-8-15(13)24-18/h2-10H,1H3,(H,22,23)

InChI Key

PTRHJBXRPSYDGC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02371511

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

352.84

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

5.415

Distribution Coefficient, logD

5.412

Water Solubility, LogSw

-6.01

Polar Surface Area

32.286

Acid Dissociation Constant (pKa)

9.58

Base Dissociation Constant (pKb)

4.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.30

8377-1555 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Targets:
  • Proteases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with 8377-1555 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8377-1555?
Check Price and Availability of 8377-1555, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8377-1555 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8377-1555
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8377-1555
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8377-1555 available by request