8525-0131 Screening compound: 2-(2,3-dimethylphenyl)-4,4,6,8-tetramethyl-1H,2H,4H,5H-[1,2]thiazolo[5,4-c]quinoline-1-thione

8525-0131 Screening compound: 2-(2,3-dimethylphenyl)-4,4,6,8-tetramethyl-1H,2H,4H,5H-[1,2]thiazolo[5,4-c]quinoline-1-thione
8525-0131 Screening compound: 2-(2,3-dimethylphenyl)-4,4,6,8-tetramethyl-1H,2H,4H,5H-[1,2]thiazolo[5,4-c]quinoline-1-thione alternative view

Chemical Structure Depiction of ChemDiv screening compound 8525-0131
2-(2,3-dimethylphenyl)-4,4,6,8-tetramethyl-1H,2H,4H,5H-[1,2]thiazolo[5,4-c]quinoline-1-thione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

8525-0131

Molecular Formula

C22H24N2S2 (C22 H24 N2 S2)

Compound Name

2-(2,3-dimethylphenyl)-4,4,6,8-tetramethyl-1H,2H,4H,5H-[1,2]thiazolo[5,4-c]quinoline-1-thione

IUPAC name

2-(23-dimethylphenyl)-4468-tetramethyl-1H2H4H5H-[12]thiazolo[54-c]quinoline-1-thione

SMILES

CC1(C)Nc(c(C)cc(C)c2)c2C(C2=S)=C1SN2c1c(C)c(C)ccc1

InChI

InChI=1S/C22H24N2S2/c1-12-10-14(3)19-16(11-12)18-20(22(5,6)23-19)26-24(21(18)25)17-9-7-8-13(2)15(17)4/h7-11,23H,1-6H3

InChI Key

SDAZHWWYWRTSSF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08075598

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

380.58

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

1.00

Number of Nitrogen and Oxygen Atoms

2

Partition Coefficient, logP

6.234

Distribution Coefficient, logD

6.078

Water Solubility, LogSw

-5.95

Polar Surface Area

12.153

Acid Dissociation Constant (pKa)

17.68

Base Dissociation Constant (pKb)

-1.94

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.80

8525-0131 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with 8525-0131 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound 8525-0131?
Check Price and Availability of 8525-0131, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of 8525-0131 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for 8525-0131
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for 8525-0131
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of 8525-0131 available by request