8525-0158 Screening compound: 5-bromo-1,2,3',4'-tetrahydro-1'H-spiro[indole-3,2'-quinazoline]-2,4'-dione
Chemical Structure Depiction of ChemDiv screening compound 8525-0158
5-bromo-1,2,3',4'-tetrahydro-1'H-spiro[indole-3,2'-quinazoline]-2,4'-dione
Available from 1 mg
Formats:
- Glass Vials (4ml Glass Vials VWR #97047-678)
- 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)
Shiptime: 1 week worldwide delivery in most cases
Compound Identifiers
ChemDiv Compound ID
8525-0158
Molecular Formula
C15H10BrN3O2 (C15 H10 BrN3 O2)
Compound Name
5-bromo-1,2,3',4'-tetrahydro-1'H-spiro[indole-3,2'-quinazoline]-2,4'-dione
IUPAC name
5-bromo-123'4'-tetrahydro-1'H-spiro[indole-32'-quinazoline]-24'-dione
SMILES
O=C(C1(Nc2c3cccc2)NC3=O)Nc(cc2)c1cc2Br
InChI Key
MDL Number (MFCD)
Chemical and Physical Properties
Saltdata
n/a
Molecular Weight
344.17
Hydrogen Bond Acceptors Count
4.00
Hydrogen Bond Donors Count
3.00
Rotatable Bond Count
0.00
Number of Nitrogen and Oxygen Atoms
5
Partition Coefficient, logP
2.700
Distribution Coefficient, logD
2.699
Water Solubility, LogSw
-3.58
Polar Surface Area
62.426
Acid Dissociation Constant (pKa)
9.99
Base Dissociation Constant (pKb)
-0.89
Number of Chiral Centers
1.00
Percent sp3 carbon bonding
6.70
8525-0158 in Drug Discovery
Included in Screening Libraries
Antiviral HBV Library (10007 compounds)
Antiviral Library (67538 compounds)
Human Transcription Factors Annotated Library (5098 compounds)
Protein Arginine Methyltransferases Library (27925 compounds)
Protein-Protein Interaction Library (218420 compounds)
Selective Target Activity Profiling Library (14702 compounds)
Spiro Library (21655 compounds)
Voltage-Gated Ion Channel-Targeted Library (4740 compounds)
Akt-Targeted Library (14764 compounds)
Beyond the Flatland Library sp3 enriched (92988 compounds)
ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)
MDM2-p53 interaction inhibitors Library (21687 compounds)
New Agro Library (44492 compounds)
Included in 1.7M Stock Database
- Antiviral
- Infections
- Immune system
- Antiviral
- Infections
- Immune system
- Cancer
- Musculoskeletal
- Digestive system
- Respiratory tract
- Male
- Female
- Hemic and lymphatic
- Metabolic
- Nervous system
- Digestive system
- Respiratory tract
- Male
- Female
- Hemic and lymphatic
- Skin
- Cancer
- Others
- Ion Channels
- Kinases
- Epigenetic
- PPI modulators
- PPI modulators
- PPI modulators
- Cyclic compounds
- Cyclic compounds
- Agro
References: we are preparing a list of scientific research reports with 8525-0158 chemical compound. It will be published here after verification.
Frequently Asked Questions
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Available from 1 mg in Glass Vials or 96-tube racks.
ChemDiv sends parcels with Express services (UPS, WC).
- 1–2 days for small orders
- 2–4 weeks for large selections
- 0.5–50 mg of dry powder sample in single glass vials, custom vials
- DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)