A0005706 Screening compound: 1-[5-(4-chlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl]-4-phenylpiperazine

A0005706 Screening compound: 1-[5-(4-chlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl]-4-phenylpiperazine
A0005706 Screening compound: 1-[5-(4-chlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl]-4-phenylpiperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound A0005706
1-[5-(4-chlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl]-4-phenylpiperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

A0005706

Molecular Formula

C24H19ClF3N5O (C24 H19 ClF3 N5 O)

Compound Name

1-[5-(4-chlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl]-4-phenylpiperazine

IUPAC name

1-[5-(4-chlorophenyl)-7-(trifluoromethyl)pyrazolo[15-a]pyrimidine-2-carbonyl]-4-phenylpiperazine

SMILES

O=C(c1nn2c(C(F)(F)F)cc(-c(cc3)ccc3Cl)nc2c1)N(CC1)CCN1c1ccccc1

InChI

InChI=1S/C24H19ClF3N5O/c25-17-8-6-16(7-9-17)19-14-21(24(26,27)28)33-22(29-19)15-20(30-33)23(34)32-12-10-31(11-13-32)18-4-2-1-3-5-18/h1-9,14-15H,10-13H2

InChI Key

XDQWTEOFCAOZKJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD01529530

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

485.9

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.499

Distribution Coefficient, logD

5.499

Water Solubility, LogSw

-6.13

Polar Surface Area

38.306

Acid Dissociation Constant (pKa)

28.47

Base Dissociation Constant (pKb)

3.66

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.80

A0005706 in Drug Discovery

Included in Screening Libraries

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with A0005706 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound A0005706?
Check Price and Availability of A0005706, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of A0005706 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for A0005706
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for A0005706
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of A0005706 available by request