C127-0214 Screening compound: 6-methoxy-2-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}-1,3-benzothiazole

C127-0214 Screening compound: 6-methoxy-2-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}-1,3-benzothiazole
C127-0214 Screening compound: 6-methoxy-2-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}-1,3-benzothiazole alternative view

Chemical Structure Depiction of ChemDiv screening compound C127-0214
6-methoxy-2-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}-1,3-benzothiazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C127-0214

Molecular Formula

C23H27N5O2S (C23 H27 N5 O2 S)

Compound Name

6-methoxy-2-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}-1,3-benzothiazole

IUPAC name

6-methoxy-2-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]piperidin-1-yl}-13-benzothiazole

SMILES

COc(cc1)cc2c1nc(N(CC1)CCC1C(N(CC1)CCN1c1ncccc1)=O)s2

InChI

InChI=1S/C23H27N5O2S/c1-30-18-5-6-19-20(16-18)31-23(25-19)28-10-7-17(8-11-28)22(29)27-14-12-26(13-15-27)21-4-2-3-9-24-21/h2-6,9,16-17H,7-8,10-15H2,1H3

InChI Key

CKPBZVKLBNABPL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14721139

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

437.57

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.110

Distribution Coefficient, logD

4.101

Water Solubility, LogSw

-4.30

Polar Surface Area

49.190

Acid Dissociation Constant (pKa)

21.91

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

43.50

C127-0214 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

SmartTM Library (51161 compounds)

Therapeutical Diversity Annotated Library (7563 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with C127-0214 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C127-0214?
Check Price and Availability of C127-0214, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C127-0214 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C127-0214
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C127-0214
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C127-0214 available by request