C130-0358 Screening compound: 2-methoxy-4-[2-(4-methylpiperazino)-6-(trifluoromethyl)-4-pyrimidinyl]phenyl methyl ether

C130-0358 Screening compound: 2-methoxy-4-[2-(4-methylpiperazino)-6-(trifluoromethyl)-4-pyrimidinyl]phenyl methyl ether
C130-0358 Screening compound: 2-methoxy-4-[2-(4-methylpiperazino)-6-(trifluoromethyl)-4-pyrimidinyl]phenyl methyl ether alternative view

Chemical Structure Depiction of ChemDiv screening compound C130-0358
2-methoxy-4-[2-(4-methylpiperazino)-6-(trifluoromethyl)-4-pyrimidinyl]phenyl methyl ether

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C130-0358

Molecular Formula

C18H21F3N4O2 (C18 H21 F3 N4 O2)

Compound Name

2-methoxy-4-[2-(4-methylpiperazino)-6-(trifluoromethyl)-4-pyrimidinyl]phenyl methyl ether

IUPAC name

n/a

SMILES

CN(CC1)CCN1c1nc(-c(cc2)cc(OC)c2OC)cc(C(F)(F)F)n1

InChI

InChI=1S/C18H21F3N4O2/c1-24-6-8-25(9-7-24)17-22-13(11-16(23-17)18(19,20)21)12-4-5-14(26-2)15(10-12)27-3/h4-5,10-11H,6-9H2,1-3H3

InChI Key

QZTGRXWLETZUEB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05029100

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

382.39

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.608

Distribution Coefficient, logD

3.037

Water Solubility, LogSw

-3.80

Polar Surface Area

39.655

Acid Dissociation Constant (pKa)

20.58

Base Dissociation Constant (pKb)

7.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.44

C130-0358 in Drug Discovery

Included in Screening Libraries

Anti-infective Library (19449 compounds)

CNS targets activity set (6557 compounds)

Akt-Targeted Library (14764 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with C130-0358 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C130-0358?
Check Price and Availability of C130-0358, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C130-0358 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C130-0358
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C130-0358
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C130-0358 available by request