C137-2287 Screening compound: 5-bromo-1-cyclopropanecarbonyl-N-(diphenylmethyl)-2,3-dihydro-1H-indole-6-sulfonamide

C137-2287 Screening compound: 5-bromo-1-cyclopropanecarbonyl-N-(diphenylmethyl)-2,3-dihydro-1H-indole-6-sulfonamide
C137-2287 Screening compound: 5-bromo-1-cyclopropanecarbonyl-N-(diphenylmethyl)-2,3-dihydro-1H-indole-6-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C137-2287
5-bromo-1-cyclopropanecarbonyl-N-(diphenylmethyl)-2,3-dihydro-1H-indole-6-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C137-2287

Molecular Formula

C25H23BrN2O3S (C25 H23 BrN2 O3 S)

Compound Name

5-bromo-1-cyclopropanecarbonyl-N-(diphenylmethyl)-2,3-dihydro-1H-indole-6-sulfonamide

IUPAC name

5-bromo-1-cyclopropanecarbonyl-N-(diphenylmethyl)-23-dihydro-1H-indole-6-sulfonamide

SMILES

O=C(C1CC1)N(CCc1c2)c1cc(S(NC(c1ccccc1)c1ccccc1)(=O)=O)c2Br

InChI

InChI=1S/C25H23BrN2O3S/c26-21-15-20-13-14-28(25(29)19-11-12-19)22(20)16-23(21)32(30,31)27-24(17-7-3-1-4-8-17)18-9-5-2-6-10-18/h1-10,15-16,19,24,27H,11-14H2

InChI Key

USZMMNPQSMCZAM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14721763

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

511.44

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.016

Distribution Coefficient, logD

5.013

Water Solubility, LogSw

-4.81

Polar Surface Area

57.493

Acid Dissociation Constant (pKa)

9.61

Base Dissociation Constant (pKb)

-1.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

C137-2287 in Drug Discovery

Included in Screening Libraries

DGK Inhibitors Library (10558 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with C137-2287 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C137-2287?
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What is the minimum amount of C137-2287 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C137-2287
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C137-2287
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C137-2287 available by request