C138-1983 Screening compound: (2E)-3-(3-chlorophenyl)-N-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]prop-2-enamide

C138-1983 Screening compound: (2E)-3-(3-chlorophenyl)-N-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]prop-2-enamide
C138-1983 Screening compound: (2E)-3-(3-chlorophenyl)-N-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]prop-2-enamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C138-1983
(2E)-3-(3-chlorophenyl)-N-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]prop-2-enamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C138-1983

Molecular Formula

C24H25ClN4O (C24 H25 ClN4 O)

Compound Name

(2E)-3-(3-chlorophenyl)-N-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]prop-2-enamide

IUPAC name

(2E)-3-(3-chlorophenyl)-N-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]prop-2-enamide

SMILES

Cc1c(cc(cc2)NC(/C=C/c3cccc(Cl)c3)=O)c2nc(N2CCN(C)CC2)c1

InChI

InChI=1S/C24H25ClN4O/c1-17-14-23(29-12-10-28(2)11-13-29)27-22-8-7-20(16-21(17)22)26-24(30)9-6-18-4-3-5-19(25)15-18/h3-9,14-16H,10-13H2,1-2H3,(H,26,30)

InChI Key

GQWRCNJAHPBIRB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14722175

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

420.94

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.631

Distribution Coefficient, logD

5.061

Water Solubility, LogSw

-5.99

Polar Surface Area

37.839

Acid Dissociation Constant (pKa)

11.32

Base Dissociation Constant (pKb)

7.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

C138-1983 in Drug Discovery

Included in Screening Libraries

Human GPCR Annotated Library (5539 compounds)

Nucleic Acid Ligands (8311 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Epigenetics Focused Set (26518 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with C138-1983 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C138-1983?
Check Price and Availability of C138-1983, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C138-1983 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C138-1983
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C138-1983
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C138-1983 available by request