C188-0323 Screening compound: N-[2-(thiophen-2-yl)imidazo[1,2-a]pyridin-3-yl]cyclohexanecarboxamide

C188-0323 Screening compound: N-[2-(thiophen-2-yl)imidazo[1,2-a]pyridin-3-yl]cyclohexanecarboxamide
C188-0323 Screening compound: N-[2-(thiophen-2-yl)imidazo[1,2-a]pyridin-3-yl]cyclohexanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C188-0323
N-[2-(thiophen-2-yl)imidazo[1,2-a]pyridin-3-yl]cyclohexanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C188-0323

Molecular Formula

C18H19N3OS (C18 H19 N3 OS)

Compound Name

N-[2-(thiophen-2-yl)imidazo[1,2-a]pyridin-3-yl]cyclohexanecarboxamide

IUPAC name

N-[2-(thiophen-2-yl)imidazo[12-a]pyridin-3-yl]cyclohexanecarboxamide

SMILES

O=C(C1CCCCC1)Nc1c(-c2cccs2)nc2n1cccc2

InChI

InChI=1S/C18H19N3OS/c22-18(13-7-2-1-3-8-13)20-17-16(14-9-6-12-23-14)19-15-10-4-5-11-21(15)17/h4-6,9-13H,1-3,7-8H2,(H,20,22)

InChI Key

KRACAVRTMRDXHB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04460006

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

325.43

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.936

Distribution Coefficient, logD

3.936

Water Solubility, LogSw

-3.93

Polar Surface Area

33.068

Acid Dissociation Constant (pKa)

12.54

Base Dissociation Constant (pKb)

2.45

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

C188-0323 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with C188-0323 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C188-0323?
Check Price and Availability of C188-0323, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C188-0323 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C188-0323
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C188-0323
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C188-0323 available by request