C188-0542 Screening compound: 5-bromo-2-chloro-N-[2-(3,4-dimethoxyphenyl)-7-methylimidazo[1,2-a]pyridin-3-yl]benzamide

C188-0542 Screening compound: 5-bromo-2-chloro-N-[2-(3,4-dimethoxyphenyl)-7-methylimidazo[1,2-a]pyridin-3-yl]benzamide
C188-0542 Screening compound: 5-bromo-2-chloro-N-[2-(3,4-dimethoxyphenyl)-7-methylimidazo[1,2-a]pyridin-3-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C188-0542
5-bromo-2-chloro-N-[2-(3,4-dimethoxyphenyl)-7-methylimidazo[1,2-a]pyridin-3-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C188-0542

Molecular Formula

C23H19BrClN3O3 (C23 H19 BrClN3 O3)

Compound Name

5-bromo-2-chloro-N-[2-(3,4-dimethoxyphenyl)-7-methylimidazo[1,2-a]pyridin-3-yl]benzamide

IUPAC name

5-bromo-2-chloro-N-[2-(34-dimethoxyphenyl)-7-methylimidazo[12-a]pyridin-3-yl]benzamide

SMILES

Cc1cc2nc(-c(cc3)cc(OC)c3OC)c(NC(c(cc(cc3)Br)c3Cl)=O)n2cc1

InChI

InChI=1S/C23H19BrClN3O3/c1-13-8-9-28-20(10-13)26-21(14-4-7-18(30-2)19(11-14)31-3)22(28)27-23(29)16-12-15(24)5-6-17(16)25/h4-12H,1-3H3,(H,27,29)

InChI Key

VUHSBTCOPGZRDN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04460090

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

500.78

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.322

Distribution Coefficient, logD

5.321

Water Solubility, LogSw

-5.86

Polar Surface Area

47.119

Acid Dissociation Constant (pKa)

9.94

Base Dissociation Constant (pKb)

3.57

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.00

C188-0542 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with C188-0542 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C188-0542?
Check Price and Availability of C188-0542, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C188-0542 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C188-0542
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C188-0542
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C188-0542 available by request