C200-1447 Screening compound: 1-(2-chloropyridin-3-yl)-3-(2-methoxybenzoyl)thiourea

C200-1447 Screening compound: 1-(2-chloropyridin-3-yl)-3-(2-methoxybenzoyl)thiourea
C200-1447 Screening compound: 1-(2-chloropyridin-3-yl)-3-(2-methoxybenzoyl)thiourea alternative view

Chemical Structure Depiction of ChemDiv screening compound C200-1447
1-(2-chloropyridin-3-yl)-3-(2-methoxybenzoyl)thiourea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C200-1447

Molecular Formula

C14H12ClN3O2S (C14 H12 ClN3 O2 S)

Compound Name

1-(2-chloropyridin-3-yl)-3-(2-methoxybenzoyl)thiourea

IUPAC name

1-(2-chloropyridin-3-yl)-3-(2-methoxybenzoyl)thiourea

SMILES

COc(cccc1)c1C(NC(Nc1cccnc1Cl)=S)=O

InChI

InChI=1S/C14H12ClN3O2S/c1-20-11-7-3-2-5-9(11)13(19)18-14(21)17-10-6-4-8-16-12(10)15/h2-8H,1H3,(H2,17,18,19,21)

InChI Key

ZCKLACTUTMWGMO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD04445182

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

321.79

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.707

Distribution Coefficient, logD

2.514

Water Solubility, LogSw

-3.73

Polar Surface Area

49.858

Acid Dissociation Constant (pKa)

7.65

Base Dissociation Constant (pKb)

0.03

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

7.10

C200-1447 in Drug Discovery

Included in Screening Libraries

Antiviral Annotated Library (21441 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Human Receptors Annotated Library (5376 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with C200-1447 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C200-1447?
Check Price and Availability of C200-1447, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C200-1447 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C200-1447
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C200-1447
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C200-1447 available by request