C200-5102 Screening compound: 1-(3-chlorobenzyl)-3'-[3-(trifluoromethyl)phenyl]-4'H-spiro[indole-3,2'-[1,3]thiazolidine]-2,4'(1H)-dione 1',1'-dioxide

C200-5102 Screening compound: 1-(3-chlorobenzyl)-3'-[3-(trifluoromethyl)phenyl]-4'H-spiro[indole-3,2'-[1,3]thiazolidine]-2,4'(1H)-dione 1',1'-dioxide
C200-5102 Screening compound: 1-(3-chlorobenzyl)-3'-[3-(trifluoromethyl)phenyl]-4'H-spiro[indole-3,2'-[1,3]thiazolidine]-2,4'(1H)-dione 1',1'-dioxide alternative view

Chemical Structure Depiction of ChemDiv screening compound C200-5102
1-(3-chlorobenzyl)-3'-[3-(trifluoromethyl)phenyl]-4'H-spiro[indole-3,2'-[1,3]thiazolidine]-2,4'(1H)-dione 1',1'-dioxide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C200-5102

Molecular Formula

C24H16ClF3N2O4S (C24 H16 ClF3 N2 O4 S)

Compound Name

1-(3-chlorobenzyl)-3'-[3-(trifluoromethyl)phenyl]-4'H-spiro[indole-3,2'-[1,3]thiazolidine]-2,4'(1H)-dione 1',1'-dioxide

IUPAC name

1-[(3-chlorophenyl)methyl]-3'-[3-(trifluoromethyl)phenyl]-12-dihydrospiro[indole-32'-[1lambda63]thiazolidine]-1'1'24'-tetrone

SMILES

O=C(CS(C1(c(cccc2)c2N2Cc3cccc(Cl)c3)C2=O)(=O)=O)N1c1cc(C(F)(F)F)ccc1

InChI

InChI=1S/C24H16ClF3N2O4S/c25-17-7-3-5-15(11-17)13-29-20-10-2-1-9-19(20)23(22(29)32)30(21(31)14-35(23,33)34)18-8-4-6-16(12-18)24(26,27)28/h1-12H,13-14H2/t23-/m0/s1

InChI Key

GZSXUBQVAYVWEK-QHCPKHFHSA-N

MDL Number (MFCD)

MFCD14727754

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

520.92

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.561

Distribution Coefficient, logD

0.881

Water Solubility, LogSw

-4.64

Polar Surface Area

59.535

Acid Dissociation Constant (pKa)

3.72

Base Dissociation Constant (pKb)

-7.88

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

16.70

C200-5102 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with C200-5102 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C200-5102?
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What is the minimum amount of C200-5102 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C200-5102
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C200-5102
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C200-5102 available by request