C204-0018 Screening compound: N'-(2,4-difluorophenyl)-N-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]butanediamide

C204-0018 Screening compound: N'-(2,4-difluorophenyl)-N-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]butanediamide
C204-0018 Screening compound: N'-(2,4-difluorophenyl)-N-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]butanediamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C204-0018
N'-(2,4-difluorophenyl)-N-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]butanediamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C204-0018

Molecular Formula

C24H24F2N4O3 (C24 H24 F2 N4 O3)

Compound Name

N'-(2,4-difluorophenyl)-N-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]butanediamide

IUPAC name

N'-(24-difluorophenyl)-N-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]butanediamide

SMILES

Cc1c(cc(cc2)NC(CCC(Nc(ccc(F)c3)c3F)=O)=O)c2nc(N2CCOCC2)c1

InChI

InChI=1S/C24H24F2N4O3/c1-15-12-22(30-8-10-33-11-9-30)28-20-5-3-17(14-18(15)20)27-23(31)6-7-24(32)29-21-4-2-16(25)13-19(21)26/h2-5,12-14H,6-11H2,1H3,(H,27,31)(H,29,32)

InChI Key

OELAJJRBJSOIHT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14731916

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

454.48

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.544

Distribution Coefficient, logD

3.526

Water Solubility, LogSw

-3.68

Polar Surface Area

64.723

Acid Dissociation Constant (pKa)

8.77

Base Dissociation Constant (pKb)

4.21

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

C204-0018 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with C204-0018 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C204-0018?
Check Price and Availability of C204-0018, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C204-0018 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C204-0018
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C204-0018
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C204-0018 available by request