C218-0344 Screening compound: 3-[4-(5-chloro-2-methylphenyl)piperazine-1-carbonyl]-6-[(2-fluorophenyl)methyl]-5-methylpyrazolo[1,5-a]pyrimidin-7-ol

C218-0344 Screening compound: 3-[4-(5-chloro-2-methylphenyl)piperazine-1-carbonyl]-6-[(2-fluorophenyl)methyl]-5-methylpyrazolo[1,5-a]pyrimidin-7-ol
C218-0344 Screening compound: 3-[4-(5-chloro-2-methylphenyl)piperazine-1-carbonyl]-6-[(2-fluorophenyl)methyl]-5-methylpyrazolo[1,5-a]pyrimidin-7-ol alternative view

Chemical Structure Depiction of ChemDiv screening compound C218-0344
3-[4-(5-chloro-2-methylphenyl)piperazine-1-carbonyl]-6-[(2-fluorophenyl)methyl]-5-methylpyrazolo[1,5-a]pyrimidin-7-ol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C218-0344

Molecular Formula

C26H25ClFN5O2 (C26 H25 ClFN5 O2)

Compound Name

3-[4-(5-chloro-2-methylphenyl)piperazine-1-carbonyl]-6-[(2-fluorophenyl)methyl]-5-methylpyrazolo[1,5-a]pyrimidin-7-ol

IUPAC name

3-[4-(5-chloro-2-methylphenyl)piperazine-1-carbonyl]-6-[(2-fluorophenyl)methyl]-5-methylpyrazolo[15-a]pyrimidin-7-ol

SMILES

Cc(ccc(Cl)c1)c1N(CC1)CCN1C(c(cnn12)c2nc(C)c(Cc(cccc2)c2F)c1O)=O

InChI

InChI=1S/C26H25ClFN5O2/c1-16-7-8-19(27)14-23(16)31-9-11-32(12-10-31)25(34)21-15-29-33-24(21)30-17(2)20(26(33)35)13-18-5-3-4-6-22(18)28/h3-8,14-15,35H,9-13H2,1-2H3

InChI Key

LKOJFUWDJWBEQX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14732504

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

493.97

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.707

Distribution Coefficient, logD

3.638

Water Solubility, LogSw

-4.69

Polar Surface Area

55.531

Acid Dissociation Constant (pKa)

6.37

Base Dissociation Constant (pKb)

2.13

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.90

C218-0344 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with C218-0344 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C218-0344?
Check Price and Availability of C218-0344, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C218-0344 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C218-0344
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C218-0344
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C218-0344 available by request