C224-1434 Screening compound: 1-[(4-chlorophenyl)(phenyl)methyl]-4-[1-(thiophene-2-sulfonyl)piperidine-4-carbonyl]piperazine

C224-1434 Screening compound: 1-[(4-chlorophenyl)(phenyl)methyl]-4-[1-(thiophene-2-sulfonyl)piperidine-4-carbonyl]piperazine
C224-1434 Screening compound: 1-[(4-chlorophenyl)(phenyl)methyl]-4-[1-(thiophene-2-sulfonyl)piperidine-4-carbonyl]piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound C224-1434
1-[(4-chlorophenyl)(phenyl)methyl]-4-[1-(thiophene-2-sulfonyl)piperidine-4-carbonyl]piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C224-1434

Molecular Formula

C27H30ClN3O3S2 (C27 H30 ClN3 O3 S2)

Compound Name

1-[(4-chlorophenyl)(phenyl)methyl]-4-[1-(thiophene-2-sulfonyl)piperidine-4-carbonyl]piperazine

IUPAC name

1-[(4-chlorophenyl)(phenyl)methyl]-4-[1-(thiophene-2-sulfonyl)piperidine-4-carbonyl]piperazine

SMILES

O=C(C(CC1)CCN1S(c1cccs1)(=O)=O)N(CC1)CCN1C(c1ccccc1)c(cc1)ccc1Cl

InChI

InChI=1S/C27H30ClN3O3S2/c28-24-10-8-22(9-11-24)26(21-5-2-1-3-6-21)29-16-18-30(19-17-29)27(32)23-12-14-31(15-13-23)36(33,34)25-7-4-20-35-25/h1-11,20,23,26H,12-19H2/t26-/m0/s1

InChI Key

JKULJUMNNVOINP-SANMLTNESA-N

MDL Number (MFCD)

MFCD14732644

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

544.14

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.806

Distribution Coefficient, logD

4.804

Water Solubility, LogSw

-5.26

Polar Surface Area

52.177

Acid Dissociation Constant (pKa)

23.63

Base Dissociation Constant (pKb)

4.96

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

37.00

C224-1434 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

DGK Inhibitors Library (10558 compounds)

GPCR Targeted Library (31838 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with C224-1434 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C224-1434?
Check Price and Availability of C224-1434, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C224-1434 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C224-1434
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C224-1434
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C224-1434 available by request