C226-1499 Screening compound: 3-{3-[4-(diphenylmethyl)piperazine-1-carbonyl]-1,2-oxazol-5-yl}phenol

C226-1499 Screening compound: 3-{3-[4-(diphenylmethyl)piperazine-1-carbonyl]-1,2-oxazol-5-yl}phenol
C226-1499 Screening compound: 3-{3-[4-(diphenylmethyl)piperazine-1-carbonyl]-1,2-oxazol-5-yl}phenol alternative view

Chemical Structure Depiction of ChemDiv screening compound C226-1499
3-{3-[4-(diphenylmethyl)piperazine-1-carbonyl]-1,2-oxazol-5-yl}phenol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C226-1499

Molecular Formula

C27H25N3O3 (C27 H25 N3 O3)

Compound Name

3-{3-[4-(diphenylmethyl)piperazine-1-carbonyl]-1,2-oxazol-5-yl}phenol

IUPAC name

3-{3-[4-(diphenylmethyl)piperazine-1-carbonyl]-12-oxazol-5-yl}phenol

SMILES

Oc1cccc(-c2cc(C(N(CC3)CCN3C(c3ccccc3)c3ccccc3)=O)no2)c1

InChI

InChI=1S/C27H25N3O3/c31-23-13-7-12-22(18-23)25-19-24(28-33-25)27(32)30-16-14-29(15-17-30)26(20-8-3-1-4-9-20)21-10-5-2-6-11-21/h1-13,18-19,26,31H,14-17H2

InChI Key

MVOAMHJMSMWMRC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09782419

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

439.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.867

Distribution Coefficient, logD

4.861

Water Solubility, LogSw

-4.43

Polar Surface Area

58.600

Acid Dissociation Constant (pKa)

9.35

Base Dissociation Constant (pKb)

4.98

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.50

C226-1499 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

CNS targets activity set (6557 compounds)

DGK Inhibitors Library (10558 compounds)

Carbonic Anhydrase II Library (4939 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Ion Channels

References: we are preparing a list of scientific research reports with C226-1499 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C226-1499?
Check Price and Availability of C226-1499, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C226-1499 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C226-1499
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C226-1499
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C226-1499 available by request