C260-0734 Screening compound: 2-{7-chloro-3-[(furan-2-yl)methyl]-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-1-yl}-N-(5-methyl-1H-pyrazol-3-yl)acetamide

C260-0734 Screening compound: 2-{7-chloro-3-[(furan-2-yl)methyl]-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-1-yl}-N-(5-methyl-1H-pyrazol-3-yl)acetamide
C260-0734 Screening compound: 2-{7-chloro-3-[(furan-2-yl)methyl]-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-1-yl}-N-(5-methyl-1H-pyrazol-3-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C260-0734
2-{7-chloro-3-[(furan-2-yl)methyl]-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-1-yl}-N-(5-methyl-1H-pyrazol-3-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C260-0734

Molecular Formula

C19H16ClN5O4 (C19 H16 ClN5 O4)

Compound Name

2-{7-chloro-3-[(furan-2-yl)methyl]-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-1-yl}-N-(5-methyl-1H-pyrazol-3-yl)acetamide

IUPAC name

2-{7-chloro-3-[(furan-2-yl)methyl]-24-dioxo-1234-tetrahydroquinazolin-1-yl}-N-(5-methyl-1H-pyrazol-3-yl)acetamide

SMILES

Cc1cc(NC(CN(c(cc(cc2)Cl)c2C(N2Cc3ccco3)=O)C2=O)=O)n[nH]1

InChI

InChI=1S/C19H16ClN5O4/c1-11-7-16(23-22-11)21-17(26)10-24-15-8-12(20)4-5-14(15)18(27)25(19(24)28)9-13-3-2-6-29-13/h2-8H,9-10H2,1H3,(H2,21,22,23,26)

InChI Key

KTNYQMRZZIWHLY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05032131

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

413.82

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.878

Distribution Coefficient, logD

2.875

Water Solubility, LogSw

-3.58

Polar Surface Area

85.300

Acid Dissociation Constant (pKa)

9.59

Base Dissociation Constant (pKb)

0.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.80

C260-0734 in Drug Discovery

Included in Screening Libraries

GABA Library (7115 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Eye
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with C260-0734 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C260-0734?
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What is the minimum amount of C260-0734 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C260-0734
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C260-0734
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C260-0734 available by request