C260-0741 Screening compound: 7-chloro-1-(2-oxo-2-phenylethyl)-3-[(thiophen-2-yl)methyl]-1,2,3,4-tetrahydroquinazoline-2,4-dione

C260-0741 Screening compound: 7-chloro-1-(2-oxo-2-phenylethyl)-3-[(thiophen-2-yl)methyl]-1,2,3,4-tetrahydroquinazoline-2,4-dione
C260-0741 Screening compound: 7-chloro-1-(2-oxo-2-phenylethyl)-3-[(thiophen-2-yl)methyl]-1,2,3,4-tetrahydroquinazoline-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound C260-0741
7-chloro-1-(2-oxo-2-phenylethyl)-3-[(thiophen-2-yl)methyl]-1,2,3,4-tetrahydroquinazoline-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C260-0741

Molecular Formula

C21H15ClN2O3S (C21 H15 ClN2 O3 S)

Compound Name

7-chloro-1-(2-oxo-2-phenylethyl)-3-[(thiophen-2-yl)methyl]-1,2,3,4-tetrahydroquinazoline-2,4-dione

IUPAC name

7-chloro-1-(2-oxo-2-phenylethyl)-3-[(thiophen-2-yl)methyl]-1234-tetrahydroquinazoline-24-dione

SMILES

O=C(CN(c(cc(cc1)Cl)c1C(N1Cc2cccs2)=O)C1=O)c1ccccc1

InChI

InChI=1S/C21H15ClN2O3S/c22-15-8-9-17-18(11-15)23(13-19(25)14-5-2-1-3-6-14)21(27)24(20(17)26)12-16-7-4-10-28-16/h1-11H,12-13H2

InChI Key

SJJGLLHSPSKTPO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14737395

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

410.88

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.147

Distribution Coefficient, logD

4.147

Water Solubility, LogSw

-4.53

Polar Surface Area

45.532

Acid Dissociation Constant (pKa)

20.41

Base Dissociation Constant (pKb)

-10.34

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.50

C260-0741 in Drug Discovery

Included in Screening Libraries

GABA Library (7115 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Eye
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • GPCR
  • Ion Channels
  • Phosphatases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with C260-0741 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C260-0741?
Check Price and Availability of C260-0741, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C260-0741 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C260-0741
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C260-0741
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C260-0741 available by request