C260-1209 Screening compound: 3-{1-[(cyclopentylcarbamoyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl}-N-[(2-methoxyphenyl)methyl]propanamide

C260-1209 Screening compound: 3-{1-[(cyclopentylcarbamoyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl}-N-[(2-methoxyphenyl)methyl]propanamide
C260-1209 Screening compound: 3-{1-[(cyclopentylcarbamoyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl}-N-[(2-methoxyphenyl)methyl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C260-1209
3-{1-[(cyclopentylcarbamoyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl}-N-[(2-methoxyphenyl)methyl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C260-1209

Molecular Formula

C26H30N4O5 (C26 H30 N4 O5)

Compound Name

3-{1-[(cyclopentylcarbamoyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl}-N-[(2-methoxyphenyl)methyl]propanamide

IUPAC name

3-{1-[(cyclopentylcarbamoyl)methyl]-24-dioxo-1234-tetrahydroquinazolin-3-yl}-N-[(2-methoxyphenyl)methyl]propanamide

SMILES

COc1c(CNC(CCN(C(c(cccc2)c2N2CC(NC3CCCC3)=O)=O)C2=O)=O)cccc1

InChI

InChI=1S/C26H30N4O5/c1-35-22-13-7-2-8-18(22)16-27-23(31)14-15-29-25(33)20-11-5-6-12-21(20)30(26(29)34)17-24(32)28-19-9-3-4-10-19/h2,5-8,11-13,19H,3-4,9-10,14-17H2,1H3,(H,27,31)(H,28,32)

InChI Key

QJDWDJAFHHULOY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14737672

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

478.55

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.483

Distribution Coefficient, logD

2.483

Water Solubility, LogSw

-2.87

Polar Surface Area

87.910

Acid Dissociation Constant (pKa)

12.67

Base Dissociation Constant (pKb)

6.45

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.50

C260-1209 in Drug Discovery

Included in Screening Libraries

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with C260-1209 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C260-1209?
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What is the minimum amount of C260-1209 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C260-1209
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C260-1209
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C260-1209 available by request