C260-2457 Screening compound: 4-{[1-({[(furan-2-yl)methyl]carbamoyl}methyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl]methyl}-N-(3-methoxypropyl)benzamide

C260-2457 Screening compound: 4-{[1-({[(furan-2-yl)methyl]carbamoyl}methyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl]methyl}-N-(3-methoxypropyl)benzamide
C260-2457 Screening compound: 4-{[1-({[(furan-2-yl)methyl]carbamoyl}methyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl]methyl}-N-(3-methoxypropyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C260-2457
4-{[1-({[(furan-2-yl)methyl]carbamoyl}methyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl]methyl}-N-(3-methoxypropyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C260-2457

Molecular Formula

C27H28N4O6 (C27 H28 N4 O6)

Compound Name

4-{[1-({[(furan-2-yl)methyl]carbamoyl}methyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl]methyl}-N-(3-methoxypropyl)benzamide

IUPAC name

4-{[1-({[(furan-2-yl)methyl]carbamoyl}methyl)-24-dioxo-1234-tetrahydroquinazolin-3-yl]methyl}-N-(3-methoxypropyl)benzamide

SMILES

COCCCNC(c1ccc(CN(C(c(cccc2)c2N2CC(NCc3ccco3)=O)=O)C2=O)cc1)=O

InChI

InChI=1S/C27H28N4O6/c1-36-14-5-13-28-25(33)20-11-9-19(10-12-20)17-31-26(34)22-7-2-3-8-23(22)30(27(31)35)18-24(32)29-16-21-6-4-15-37-21/h2-4,6-12,15H,5,13-14,16-18H2,1H3,(H,28,33)(H,29,32)

InChI Key

VCHCZJBBNQQQNC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14738626

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

504.54

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

13.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.238

Distribution Coefficient, logD

2.238

Water Solubility, LogSw

-2.97

Polar Surface Area

96.356

Acid Dissociation Constant (pKa)

13.15

Base Dissociation Constant (pKb)

-1.81

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.90

C260-2457 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Dark Chemical Matter Library (18430 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Structure:
  • Pool
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with C260-2457 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C260-2457?
Check Price and Availability of C260-2457, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C260-2457 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C260-2457
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C260-2457
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C260-2457 available by request