C267-0078 Screening compound: N-[2-(4-ethylpiperazin-1-yl)-4-methylquinolin-6-yl]-4-(pyridin-2-yl)piperazine-1-carbothioamide

C267-0078 Screening compound: N-[2-(4-ethylpiperazin-1-yl)-4-methylquinolin-6-yl]-4-(pyridin-2-yl)piperazine-1-carbothioamide
C267-0078 Screening compound: N-[2-(4-ethylpiperazin-1-yl)-4-methylquinolin-6-yl]-4-(pyridin-2-yl)piperazine-1-carbothioamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C267-0078
N-[2-(4-ethylpiperazin-1-yl)-4-methylquinolin-6-yl]-4-(pyridin-2-yl)piperazine-1-carbothioamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C267-0078

Molecular Formula

C26H33N7S (C26 H33 N7 S)

Compound Name

N-[2-(4-ethylpiperazin-1-yl)-4-methylquinolin-6-yl]-4-(pyridin-2-yl)piperazine-1-carbothioamide

IUPAC name

N-[2-(4-ethylpiperazin-1-yl)-4-methylquinolin-6-yl]-4-(pyridin-2-yl)piperazine-1-carbothioamide

SMILES

CCN(CC1)CCN1c1cc(C)c(cc(cc2)NC(N(CC3)CCN3c3ncccc3)=S)c2n1

InChI

InChI=1S/C26H33N7S/c1-3-30-10-12-32(13-11-30)25-18-20(2)22-19-21(7-8-23(22)29-25)28-26(34)33-16-14-31(15-17-33)24-6-4-5-9-27-24/h4-9,18-19H,3,10-17H2,1-2H3,(H,28,34)

InChI Key

QJOWKGPIWPDOLH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14739488

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

475.66

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.160

Distribution Coefficient, logD

4.473

Water Solubility, LogSw

-5.16

Polar Surface Area

37.692

Acid Dissociation Constant (pKa)

13.71

Base Dissociation Constant (pKb)

7.99

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.30

C267-0078 in Drug Discovery

Included in Screening Libraries

Autophagy-Targeted Library (4564 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system

References: we are preparing a list of scientific research reports with C267-0078 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C267-0078?
Check Price and Availability of C267-0078, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C267-0078 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C267-0078
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C267-0078
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C267-0078 available by request