C267-0335 Screening compound: N-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]morpholine-4-carbothioamide

C267-0335 Screening compound: N-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]morpholine-4-carbothioamide
C267-0335 Screening compound: N-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]morpholine-4-carbothioamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C267-0335
N-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]morpholine-4-carbothioamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C267-0335

Molecular Formula

C20H27N5OS (C20 H27 N5 OS)

Compound Name

N-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]morpholine-4-carbothioamide

IUPAC name

N-[4-methyl-2-(4-methylpiperazin-1-yl)quinolin-6-yl]morpholine-4-carbothioamide

SMILES

Cc1c(cc(cc2)NC(N3CCOCC3)=S)c2nc(N2CCN(C)CC2)c1

InChI

InChI=1S/C20H27N5OS/c1-15-13-19(24-7-5-23(2)6-8-24)22-18-4-3-16(14-17(15)18)21-20(27)25-9-11-26-12-10-25/h3-4,13-14H,5-12H2,1-2H3,(H,21,27)

InChI Key

HCONLFHTIXYVBE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05027330

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

385.53

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.354

Distribution Coefficient, logD

2.784

Water Solubility, LogSw

-3.50

Polar Surface Area

33.769

Acid Dissociation Constant (pKa)

13.71

Base Dissociation Constant (pKb)

7.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

C267-0335 in Drug Discovery

Included in Screening Libraries

Dark Chemical Matter Library (18430 compounds)

Human Transcription Factors Annotated Library (5098 compounds)

PI3K-Targeted Library (17255 compounds)

Selective Target Activity Profiling Library (14702 compounds)

SmartTM Library (51161 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Structure:
  • Pool
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with C267-0335 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C267-0335?
Check Price and Availability of C267-0335, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C267-0335 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C267-0335
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C267-0335
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C267-0335 available by request