C273-0434 Screening compound: 2-{3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]-7-methylimidazo[1,2-a]pyridin-2-yl}phenol

C273-0434 Screening compound: 2-{3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]-7-methylimidazo[1,2-a]pyridin-2-yl}phenol
C273-0434 Screening compound: 2-{3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]-7-methylimidazo[1,2-a]pyridin-2-yl}phenol alternative view

Chemical Structure Depiction of ChemDiv screening compound C273-0434
2-{3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]-7-methylimidazo[1,2-a]pyridin-2-yl}phenol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C273-0434

Molecular Formula

C22H19N3O3 (C22 H19 N3 O3)

Compound Name

2-{3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]-7-methylimidazo[1,2-a]pyridin-2-yl}phenol

IUPAC name

2-{3-[(23-dihydro-14-benzodioxin-6-yl)amino]-7-methylimidazo[12-a]pyridin-2-yl}phenol

SMILES

Cc1cc2nc(-c(cccc3)c3O)c(Nc(cc3)cc4c3OCCO4)n2cc1

InChI

InChI=1S/C22H19N3O3/c1-14-8-9-25-20(12-14)24-21(16-4-2-3-5-17(16)26)22(25)23-15-6-7-18-19(13-15)28-11-10-27-18/h2-9,12-13,23,26H,10-11H2,1H3

InChI Key

PAUATIYUFAKHKS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08682455

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

373.41

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.142

Distribution Coefficient, logD

4.131

Water Solubility, LogSw

-3.79

Polar Surface Area

50.050

Acid Dissociation Constant (pKa)

9.03

Base Dissociation Constant (pKb)

4.73

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

C273-0434 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Human Proteases Annotated Library (2868 compounds)

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Selective Target Activity Profiling Library (14702 compounds)

SmartTM Library (51161 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with C273-0434 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C273-0434?
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What is the minimum amount of C273-0434 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C273-0434
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C273-0434
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C273-0434 available by request