C274-1530 Screening compound: 5-{[4-(4-benzylpiperidine-1-carbonyl)piperidin-1-yl]sulfonyl}-6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

C274-1530 Screening compound: 5-{[4-(4-benzylpiperidine-1-carbonyl)piperidin-1-yl]sulfonyl}-6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
C274-1530 Screening compound: 5-{[4-(4-benzylpiperidine-1-carbonyl)piperidin-1-yl]sulfonyl}-6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound C274-1530
5-{[4-(4-benzylpiperidine-1-carbonyl)piperidin-1-yl]sulfonyl}-6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C274-1530

Molecular Formula

C23H30N4O5S (C23 H30 N4 O5 S)

Compound Name

5-{[4-(4-benzylpiperidine-1-carbonyl)piperidin-1-yl]sulfonyl}-6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

IUPAC name

5-{[4-(4-benzylpiperidine-1-carbonyl)piperidin-1-yl]sulfonyl}-6-methyl-1234-tetrahydropyrimidine-24-dione

SMILES

CC(NC(NC1=O)=O)=C1S(N(CC1)CCC1C(N1CCC(Cc2ccccc2)CC1)=O)(=O)=O

InChI

InChI=1S/C23H30N4O5S/c1-16-20(21(28)25-23(30)24-16)33(31,32)27-13-9-19(10-14-27)22(29)26-11-7-18(8-12-26)15-17-5-3-2-4-6-17/h2-6,18-19H,7-15H2,1H3,(H2,24,25,28,30)

InChI Key

CEIRDRJIXJFFQG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14740217

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

474.58

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.750

Distribution Coefficient, logD

-1.017

Water Solubility, LogSw

-2.52

Polar Surface Area

96.860

Acid Dissociation Constant (pKa)

4.63

Base Dissociation Constant (pKb)

0.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

52.20

C274-1530 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Glucocorticoid receptors Library (4806 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Nuclear receptors
  • Proteases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with C274-1530 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C274-1530?
Check Price and Availability of C274-1530, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C274-1530 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C274-1530
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C274-1530
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C274-1530 available by request