C274-2774 Screening compound: N-(4-acetylphenyl)-1-[(5-bromo-2-thienyl)sulfonyl]-3-piperidinecarboxamide

C274-2774 Screening compound: N-(4-acetylphenyl)-1-[(5-bromo-2-thienyl)sulfonyl]-3-piperidinecarboxamide
C274-2774 Screening compound: N-(4-acetylphenyl)-1-[(5-bromo-2-thienyl)sulfonyl]-3-piperidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C274-2774
N-(4-acetylphenyl)-1-[(5-bromo-2-thienyl)sulfonyl]-3-piperidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C274-2774

Molecular Formula

C18H19BrN2O4S2 (C18 H19 BrN2 O4 S2)

Compound Name

N-(4-acetylphenyl)-1-[(5-bromo-2-thienyl)sulfonyl]-3-piperidinecarboxamide

IUPAC name

N-(4-acetylphenyl)-1-[(5-bromothiophen-2-yl)sulfonyl]piperidine-3-carboxamide

SMILES

CC(c(cc1)ccc1NC(C(CCC1)CN1S(c(s1)ccc1Br)(=O)=O)=O)=O

InChI

InChI=1S/C18H19BrN2O4S2/c1-12(22)13-4-6-15(7-5-13)20-18(23)14-3-2-10-21(11-14)27(24,25)17-9-8-16(19)26-17/h4-9,14H,2-3,10-11H2,1H3,(H,20,23)/t14-/m0/s1

InChI Key

CFOGQDDQKKTVEA-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD03829789

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

471.4

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.733

Distribution Coefficient, logD

2.729

Water Solubility, LogSw

-3.26

Polar Surface Area

69.819

Acid Dissociation Constant (pKa)

9.36

Base Dissociation Constant (pKb)

-2.49

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

33.33

C274-2774 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with C274-2774 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C274-2774?
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What is the minimum amount of C274-2774 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C274-2774
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C274-2774
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C274-2774 available by request