C274-5971 Screening compound: 2-(5-bromothiophene-2-sulfonamido)-N-[(4-methylphenyl)methyl]-3-phenylpropanamide

C274-5971 Screening compound: 2-(5-bromothiophene-2-sulfonamido)-N-[(4-methylphenyl)methyl]-3-phenylpropanamide
C274-5971 Screening compound: 2-(5-bromothiophene-2-sulfonamido)-N-[(4-methylphenyl)methyl]-3-phenylpropanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C274-5971
2-(5-bromothiophene-2-sulfonamido)-N-[(4-methylphenyl)methyl]-3-phenylpropanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C274-5971

Molecular Formula

C21H21BrN2O3S2 (C21 H21 BrN2 O3 S2)

Compound Name

2-(5-bromothiophene-2-sulfonamido)-N-[(4-methylphenyl)methyl]-3-phenylpropanamide

IUPAC name

2-(5-bromothiophene-2-sulfonamido)-N-[(4-methylphenyl)methyl]-3-phenylpropanamide

SMILES

Cc1ccc(CNC(C(Cc2ccccc2)NS(c(s2)ccc2Br)(=O)=O)=O)cc1

InChI

InChI=1S/C21H21BrN2O3S2/c1-15-7-9-17(10-8-15)14-23-21(25)18(13-16-5-3-2-4-6-16)24-29(26,27)20-12-11-19(22)28-20/h2-12,18,24H,13-14H2,1H3,(H,23,25)/t18-/m0/s1

InChI Key

KCZHXUZBASQFOD-SFHVURJKSA-N

MDL Number (MFCD)

MFCD14740410

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

493.45

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.402

Distribution Coefficient, logD

4.402

Water Solubility, LogSw

-4.27

Polar Surface Area

67.272

Acid Dissociation Constant (pKa)

10.30

Base Dissociation Constant (pKb)

-2.25

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

19.00

C274-5971 in Drug Discovery

Included in Screening Libraries

SH2 Library (10483 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Mechanism of action:
  • PPI modulators
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with C274-5971 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C274-5971?
Check Price and Availability of C274-5971, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C274-5971 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C274-5971
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C274-5971
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C274-5971 available by request