C274-8017 Screening compound: N-cyclohexyl-1-[(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)sulfonyl]piperidine-3-carboxamide

C274-8017 Screening compound: N-cyclohexyl-1-[(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)sulfonyl]piperidine-3-carboxamide
C274-8017 Screening compound: N-cyclohexyl-1-[(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)sulfonyl]piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C274-8017
N-cyclohexyl-1-[(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)sulfonyl]piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C274-8017

Molecular Formula

C17H26N4O5S (C17 H26 N4 O5 S)

Compound Name

N-cyclohexyl-1-[(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)sulfonyl]piperidine-3-carboxamide

IUPAC name

N-cyclohexyl-1-[(6-methyl-24-dioxo-1234-tetrahydropyrimidin-5-yl)sulfonyl]piperidine-3-carboxamide

SMILES

CC(NC(NC1=O)=O)=C1S(N(CCC1)CC1C(NC1CCCCC1)=O)(=O)=O

InChI

InChI=1S/C17H26N4O5S/c1-11-14(16(23)20-17(24)18-11)27(25,26)21-9-5-6-12(10-21)15(22)19-13-7-3-2-4-8-13/h12-13H,2-10H2,1H3,(H,19,22)(H2,18,20,23,24)/t12-/m0/s1

InChI Key

RBNFEEQPKGQFRP-LBPRGKRZSA-N

MDL Number (MFCD)

MFCD12217025

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

398.48

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

0.233

Distribution Coefficient, logD

-2.534

Water Solubility, LogSw

-2.08

Polar Surface Area

104.556

Acid Dissociation Constant (pKa)

4.63

Base Dissociation Constant (pKb)

4.06

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

70.59

C274-8017 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with C274-8017 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C274-8017?
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What is the minimum amount of C274-8017 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C274-8017
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C274-8017
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C274-8017 available by request