C282-0014 Screening compound: 3-[4-(4-isopropylphenyl)-6,8-dimethyl-2-morpholinopyrimido[4',5':3,4]pyrazolo[1,5-a]pyrimidin-7-yl]propanoic acid

C282-0014 Screening compound: 3-[4-(4-isopropylphenyl)-6,8-dimethyl-2-morpholinopyrimido[4',5':3,4]pyrazolo[1,5-a]pyrimidin-7-yl]propanoic acid
C282-0014 Screening compound: 3-[4-(4-isopropylphenyl)-6,8-dimethyl-2-morpholinopyrimido[4',5':3,4]pyrazolo[1,5-a]pyrimidin-7-yl]propanoic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound C282-0014
3-[4-(4-isopropylphenyl)-6,8-dimethyl-2-morpholinopyrimido[4',5':3,4]pyrazolo[1,5-a]pyrimidin-7-yl]propanoic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C282-0014

Molecular Formula

C26H30N6O3 (C26 H30 N6 O3)

Compound Name

3-[4-(4-isopropylphenyl)-6,8-dimethyl-2-morpholinopyrimido[4',5':3,4]pyrazolo[1,5-a]pyrimidin-7-yl]propanoic acid

IUPAC name

3-[46-dimethyl-11-(morpholin-4-yl)-13-[4-(propan-2-yl)phenyl]-3781012-pentaazatricyclo[7.4.0.0^{27}]trideca-13581012-hexaen-5-yl]propanoic acid

SMILES

CC(C)c(cc1)ccc1-c1nc(N2CCOCC2)nc2nn3c(C)c(CCC(O)=O)c(C)nc3c12

InChI

InChI=1S/C26H30N6O3/c1-15(2)18-5-7-19(8-6-18)23-22-24(29-26(28-23)31-11-13-35-14-12-31)30-32-17(4)20(9-10-21(33)34)16(3)27-25(22)32/h5-8,15H,9-14H2,1-4H3,(H,33,34)

InChI Key

IZKQGSPVQFZHJN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14740674

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

474.56

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.315

Distribution Coefficient, logD

1.488

Water Solubility, LogSw

-4.44

Polar Surface Area

79.322

Acid Dissociation Constant (pKa)

4.57

Base Dissociation Constant (pKb)

3.13

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.30

C282-0014 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

DGK Inhibitors Library (10558 compounds)

PI3K-Targeted Library (17255 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with C282-0014 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C282-0014?
Check Price and Availability of C282-0014, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C282-0014 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C282-0014
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C282-0014
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C282-0014 available by request