C301-8106 Screening compound: N-[4-methyl-2,6-bis(phenylamino)pyrimidin-5-yl]thiophene-2-carboxamide

C301-8106 Screening compound: N-[4-methyl-2,6-bis(phenylamino)pyrimidin-5-yl]thiophene-2-carboxamide
C301-8106 Screening compound: N-[4-methyl-2,6-bis(phenylamino)pyrimidin-5-yl]thiophene-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C301-8106
N-[4-methyl-2,6-bis(phenylamino)pyrimidin-5-yl]thiophene-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C301-8106

Molecular Formula

C22H19N5OS (C22 H19 N5 OS)

Compound Name

N-[4-methyl-2,6-bis(phenylamino)pyrimidin-5-yl]thiophene-2-carboxamide

IUPAC name

N-[4-methyl-26-bis(phenylamino)pyrimidin-5-yl]thiophene-2-carboxamide

SMILES

Cc1nc(Nc2ccccc2)nc(Nc2ccccc2)c1NC(c1cccs1)=O

InChI

InChI=1S/C22H19N5OS/c1-15-19(26-21(28)18-13-8-14-29-18)20(24-16-9-4-2-5-10-16)27-22(23-15)25-17-11-6-3-7-12-17/h2-14H,1H3,(H,26,28)(H2,23,24,25,27)

InChI Key

MVYPWFQXIAPUIN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14745242

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

401.49

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.573

Distribution Coefficient, logD

4.447

Water Solubility, LogSw

-4.38

Polar Surface Area

61.699

Acid Dissociation Constant (pKa)

10.34

Base Dissociation Constant (pKb)

6.93

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.50

C301-8106 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Antibacterial Compounds Library (13827 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Cardiovascular
  • Infections
  • Immune system
  • animal
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Proteases
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with C301-8106 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C301-8106?
Check Price and Availability of C301-8106, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C301-8106 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C301-8106
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C301-8106
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C301-8106 available by request