C340-0272 Screening compound: 4-(2-methoxyphenyl)-N-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]piperazine-1-carbothioamide

C340-0272 Screening compound: 4-(2-methoxyphenyl)-N-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]piperazine-1-carbothioamide
C340-0272 Screening compound: 4-(2-methoxyphenyl)-N-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]piperazine-1-carbothioamide alternative view

Chemical Structure Depiction of ChemDiv screening compound C340-0272
4-(2-methoxyphenyl)-N-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]piperazine-1-carbothioamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

C340-0272

Molecular Formula

C26H31N5O2S (C26 H31 N5 O2 S)

Compound Name

4-(2-methoxyphenyl)-N-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]piperazine-1-carbothioamide

IUPAC name

4-(2-methoxyphenyl)-N-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]piperazine-1-carbothioamide

SMILES

Cc1c(cc(cc2)NC(N(CC3)CCN3c(cccc3)c3OC)=S)c2nc(N2CCOCC2)c1

InChI

InChI=1S/C26H31N5O2S/c1-19-17-25(30-13-15-33-16-14-30)28-22-8-7-20(18-21(19)22)27-26(34)31-11-9-29(10-12-31)23-5-3-4-6-24(23)32-2/h3-8,17-18H,9-16H2,1-2H3,(H,27,34)

InChI Key

RJACVGXYIILRPA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14749888

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

477.63

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.172

Distribution Coefficient, logD

5.162

Water Solubility, LogSw

-5.08

Polar Surface Area

40.882

Acid Dissociation Constant (pKa)

13.71

Base Dissociation Constant (pKb)

5.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.50

C340-0272 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with C340-0272 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound C340-0272?
Check Price and Availability of C340-0272, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of C340-0272 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for C340-0272
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for C340-0272
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of C340-0272 available by request